KISS1/KISS1R expression in eutopic and ectopic endometrium of women suffering from endometriosis.

P-84: Evidence for Differential Expression of The Pluripotency Factors c-MYC, KLF4 and LIN28 in Normal Endometrium and in Endometriosis

Background Endometriosis is a common gynecological disease characterized by the presence of endometrial tissue outside the uterine cavity. This disease affects approximately 10% of women in reproductive age and is associated with pelvic pain, dysmenorrhea and infertility. The theory of involvement of stem cells is a considered new hypothesis in etiology of endometriosis.The aim of this study wa...

P-219: The Role of E-Cadherin Coding Gene (CDH1) in Pathogenesis of Endometriosis

Background: Endometriosis, a gyncological disorder,benign and common cause of infertility, is defined as the presence of endometrial glands and stroma at ectopic locations outside the uterine cavity. Clinical observations have led to the assessment that endometriosis is an invasive disease. Abnormal expression of adhesion molecules such as cadherins is likely to be an important determinant of l...

P-162: Pathophysiology of Endometriosis is Interacted by MIF, its Receptor and COX-2

Background: Endometriosis is a gynecological disease associated with severe pelvic pain and infertility. Immunological changes that occur in patients with endometriosis include reduced natural killer cell and T-lymphocyte cytotoxicity in the peritoneal fluid, and an elevated number of activated macrophages. MIF via its receptor, CD74, initiates a signaling cascade that leads to proliferation an...

The Expression of The Autophagy Gene Beclin-1 mRNA and Protein in Ectopic and Eutopic Endometrium of Patients with Endometriosis

بررسی میزان بیان ژن های کدکننده ژلاتینازها در بیماران مبتلا به آندومتریوز

Background & Aims: Endometriosis is defined as the presence of tissue resembling endometrium outside the uterine cavity. Extensive remodeling existence in peritoneal mesothelium layer is necessary for adhesion, invasion, and proliferation of endometrial fragments, which is required the activation of matrix metalloproteinase (MMPs), as a normal menstrual cycle. MMPs are a family of zinc dependen...